Read Surface Modification of Intraocular Lens Polymers by Hydrophilic Graft Polymerization for Improved Ocular Implant Biocompatibility - Ali Yahiaoui file in ePub
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Process for manufacturing an intraocular lens with an
Based on the muscle implant results, it is anticipated that the heparin surface modification of highly purified hydrogel intraocular lens materials will reduce the risk.
25 jul 2016 this hd video demonstrates problems with the bright ocular version of a cosmetic iris implant.
The intraocular implant can include a mask adapted to increase depth of focus. The method of manufacturing the implant can include positioning the mask with an aperture on a protruding pin of a positioning mold portion. The protruding pin can be configured to center the mask in the intraocular lens.
Posterior capsule opacification is one of the complications of cataract surgery caused by the adhesion and reproduction of residual human lens epithelial cells.
Surface modification of an intraocular lens material by plasma-assisted grafting with 2-hydroxyethyl methacrylate (hema), for controlled release of moxifloxacin.
11 dec 2014 cataract surgery, with damaged native lens extraction and intraocular lens (iol) implantation, is still the only currently available treatment.
Surface modification of intraocular lenses via photodynamic coating for safe and effective pco prevention overview of attention for article published in journal of materials chemistry b: materials for biology and medicine, january 2021.
As an endogenous polysaccharide, ha is widely used in ocular drug delivery systems. • combination of monoclonal antibody with ha prolongs the intravitreal half-life. • ha surface modification increases the cellular uptake and recognition of particles.
Anchorage of the ionic polymer at the surface of the silicone implant was achieved by a cycloaddition reaction of the photosensitive groups according to two options.
Two methods of surface modification of pmma, permanent and temporary, were investigated for use on intraocular lenses to reduce corneal endothelial damage.
Surface modification of intraocular lenses via photodynamic coating for safe and effective pco prevention. Posterior capsular opacification (pco) is an emerging complication in cataract phacoemulsification and intraocular lens (iol) implantation surgery, mainly stemming from the adhesion, proliferation, and trans-differentiation of the post-surgery residual lens epithelial cells (lecs).
Heparin surface modified, hydrophilic acrylic intraocular lens, hydrophobic acrylic intraocular lens.
Surface modification of silicone intraocular implants to inhibit cell proliferation.
In the past decades, physical surface modification (high-energy radiation, ultraviolet light radiation, low temperature plasma), surface coating, chemical methods (surface chemical graft and coupling, chemical immersion), heparin (hp) immobilization albumen modification and hydrophilic surface modification are methods of surface modification for biomedical materials that are employed to improve biocompatibility.
Heparin and heparin-surface-modification reduce staphylococcus epidermidis adhesion to abu el-asrar, ahmed; shibl, atef; tabbara, khalid; al-kharashi, soliman 2004-09-28 00:00:00 bacterial adherence to intraocular lenses (iols) could be the cause of endophthalmitis following cataract surgery and lens implantation. The majority of cases of postoperative endophthalmitis are caused by microflora that reside on or near the eye of the patient.
Hydrophilic modification of intraocular lens via surface initiated reversible addition-fragmentation chain transfer polymerization for reduced posterior capsular opacification.
Purpose: a heparin surface modified posterior chamber intraocular lens (iol) was compared with a conventional polymethylmethacrylate (pmma) iol regarding.
The goal is to reduce the frequency of injections that are currently given monthly or bi-monthly for the treatment of serious retinal diseases and potentially extend.
4 mar 2014 it is unclear which intraocular lens (iol) type is optimal for use in iols with or without heparin‐surface modification (hsm), with each other,.
7 feb 2021 pdf objective: this paper aimed to review the current literature on the surface modification of intraocular lenses (iols).
Surface modification with dielectric barrier discharge (dbd) plasma was carried out at atmospheric pressure (argon as the discharge gas) to improve the biocompatibility of hydrophobic acrylate intraocular lens (iol).
To improve application of hydrophobic polymethyl methacrylate intraocular lens (pmma iol) in a convenient and continuous way, 2-hydroxyethyl methacrylate surface modification of hydrophobic pmma intraocular lens by the immobilization of hydroxyethyl methacrylate for improving application in ophthalmology springerlink.
Surface modification of intraocular lenses to reduce corneal endothelial damage.
High-cylinder toric intraocular lens implantation versus combined surgery of low-cylinder intraocular lens implantation and limbal relaxing incision for high-astigmatism eyes.
25 jan 2021 previous investigations mainly focused on the hydrophilic surface modification of the iols for pco prevention, such as heparinization.
The lower fibrin-sticking rate of the iol surface was achieved by the hydrophobic and hydrophilic micro domain structures. Furthermore, it was confirmed that the fibrin-sticking rate decreased as the oh group interval was narrowed. The modified surface with the 20 μm φ domains with hydrophilic and hydrophobic was lowest in fibrin sticking.
9 jan 2014 advances in intraocular lens (iol) design have led to the use of lenses we have found that surface modification of iol surfaces chemically.
Having substituted the hydrophilic and hydrophobic groups alternately on the soft acrylic resin intraocular lens (iol) surface by using an arf excimer laser and a xe 2 excimer lamp, we have developed the iol that is free from fibrin. Acrylic resin or pmma lens has been used as an intraocular lens for 50 years.
Surface modification of iol can modify the contact stimulus of the iol material. Several studies have shown that surface modification with physical or chemical methods (without altering the main iol bulk) is a promising way to alter the surface characteristics.
Posterior capsular opacification (pco) is the most important complication in cataract phacoemulsification and intraocular lens (iol) implantation surgery, mainly stemming from the adhesion, proliferation, and transdifferentiation of the postsurgically residual lens epithelial cells (lecs). Previous investigations mainly focused on the hydrophilic surface modification of the iols for pco prevention, such as heparinization.
Corneal reshaping treatment (crt) is a non-surgical vision correction alternative. The clear front surface of the eye, using reverse geometry contact lenses. Ongoing optimal ocular health and the stability of the therapeutic effec.
The surface modification either resulted in a more hydrophobic lens, a more hydrophilic lens, or a lens with a hydrophilic anterior and hydrophobic posterior.
Collectively, our study suggests that surface modification by p(mpc-maa) can significantly improve uveal and capsular biocompatibility of hydrophobic acrylic iol, which could potentially benefit.
To investigate if the surface modification of intraocular lens (iol) is efficient in the prevention of posterior capsular opacification (pco), the acrylic surface of intraocular lens (acrysof ) was polymerized with polyethylene glycol (peg-iol). The human lens epithelial cells (1×10 4 cells/ml) were inoculated on peg grafted or unmodified acrylic lenses for the control.
Although retrospective case series have examined the use of heparin surface- modified intraocular lenses in patients with uveitis, a randomized, controlled.
Pmma has been used as an intraocular lens iol because of its high transmittance in the visible region and superb mechanical modifiability. However, protein and fat are stuck onto the lens surface after a long-term insertion, where cells proliferate; which causes the surface to get opaque, namely after-cataract.
The surface modification process uses electrical discharges or coronas to increase the bonding sites of the polymer surface for increased adhesion of inks, paints, coatings, and adhesives. The process is conducted at atmospheric pressure and is easily integrated into production lines. Specialty shaped electrodes can treat many different 3-d surfaces.
Surface modification of intraocular lens material by poly( ethylene glycol) methyl ether methacrylate via a plasma technique to influence.
The lower fibrin-sticking rate of the iol surface was achieved by the hydrophobic and hydrophilic micro domain structures. Furthermore, it was confirmed that the fibrin-sticking rate decreased as the oh group interval was narrowed. The modified surface with the 20 mm f domains with hydrophilic and hydrophobic was lowest in fibrin sticking.
17 apr 2015 cataract, and anterior segment surgeon with a practice focus on the surgical management of glaucoma, complex cataract and intraocular lens.
7 sep 2015 the cataract surgery, with damaged native lens extraction and intraocular lens ( iol) implantation, is still the only currently available treatment.
Laser-induced microstructuring of intraocular lenses apart from the efforts for light-adjustable iols, the modification of an iol’s surface with laser radiation is a subject of great interest for both physicists’ and ophthalmologists’ communities.
Results of the in vivo cataract surgery with intraocular implantation show that psbma modification on the iol surface does not induce side effects in nearby tissues, whereas posterior capsular hyperplasia can be evidently reduced.
Surface modification with dielectric barrier discharge (dbd) plasma was carried out at atmospheric pressure (argon as the discharge gas) to improve the biocompatibility of hydrophobic acrylate intraocular lens (iol). Changes of the plasma-treated iol surface in chemical composition, morphology and hydrophilicity were comprehensively evaluated by x-ray photoelectron spectroscopy (xps), field emission scanning electron microscopy (fesem), atomic force microscopy (afm) and water contact angle.
[sup][29] surface modification of iol can modify the contact stimulus of the iol material. Several studies have shown that surface modification with physical or chemical methods (without altering the main iol bulk) is a promising way to alter the surface characteristics.
Posterior capsular opacification (pco) is an emerging complication in cataract phacoemulsification and intraocular lens (iol) implantation surgery, mainly.
Surface modification of iol can modify the contact stimulus of the iol material. Several studies have shown that surface modification with physical or chemical methods(without.
We modified the surfaces of pmma-based ocular prostheses using poly (ethylene glycol) (peg), which is hydrophilic. One was a “grafting from” method, whereby peg was polymerized from the pmma surface.
Surface modification of intraocular lens with hydrophilic poly(sulfobetaine methacrylate) brush for posterior capsular opacification prevention. January 26, 2021 [ medline abstract] eyes on new product development.
Surface modification of iol to reduce the lec adhesion is of great importance in pco prevention. Herein, surface initiated reversible addition-fragmentation chain transfer (si-raft) polymerization was utilized to modify the iol materials for generating a comb-like polyethylene glycol (peg) brush coating on the surface.
Background: posterior capsular opacification (pco) is the main complication after intraocular lens (iol) implantation in cataract surgery, which is the result of lens epithelial cell (lec) adhesion, proliferation and migration on the iol and at the lens capsule interface. Hydrophilic surface modification, such as surface heparinization, decreases the cell adhesion, which has been commercialized and used clinically.
To investigate if the surface modification of intraocular lens (iol) is efficient in the prevention of posterior capsular opacification (pco), the acrylic surface of intraocular lens (acrysof) was polymerized with polyethylene glycol (peg-iol).
Results: technology of surface modification included plasma, ion beam, layer-by-layer self-assembly, ultraviolet radiation, and ozone. The main molecules introduced into iols surface were poly (ethylene glycol), polyhedral oligomeric silsesquioxane, 2-methacryloyloxyethyl phosphorylcholine, tio 2 heparin, f-heparin, titanium, titanium nitride, vinyl pyrrolidone, and inhibitors of cytokines.
Intraocular pmma lenses modified with surface-immobilized heparin: evaluation of biocompatibility in vitro and in vivo biomateriak.
Surface modified medical devices such as intraocular lens implants formed from one or more functional group-containing materials using reactive, hydrophilic polymers for the purpose of reducing or eliminating lens epithelial cell growth thereon, reducing or eliminating silicone oil absorption upon subsequent surgical exposure and/or reducing or eliminating implantation inserter friction is provided herein.
This study is aimed to investigate the use of ultrashort laser pulses to ablate the surface of intraocular lenses, and thus provide an alternative to conventional techniques. Ablation experiments were performed on hydrophilic and hydrophobic intraocular lenses (iols).
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